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According to the model of parallel reactions, two (or more) protein isoforms (E1, E2,.), each with a different level of heat resistance, exist.
In contrast to the expression profiling, in this assay more protein isoforms (52) appeared to be downregulated than upregulated (11) (Table S6).
The statistics of different GO categories presume that DNA replication and chromosome cycle genes have more protein isoforms than the average.
It has been relatively straightforward to define a 'gene' as the genomic region, which produces a given mRNA, which in turn produces one or more protein isoforms.
HTR2C has five introns and six exons, and so far it is the only G-protein binding receptor known to undergo alternative splicing of the mRNA, resulting in more protein isoforms.
Of the 20 387 protein-coding genes, 3034 gene loci have expressed sequence tag (EST) or trans-splicing evidence that they produce two or more protein isoforms, giving 24 891 coding sequence (CDS) structures in total.
Similar(52)
The data set was cleaned for redundant protein isoform sequences – if two or more protein isoform sequences from a gene are identical to one another, only one was retained.
Release 3 [ 27] of the ASD database for homo sapiens was used for the current study; the data set was cleaned for redundant protein isoform sequences – if two or more protein isoform sequences from a gene are identical to one another, only one was retained.
We considered two data sets (one from Vega and the other from ASD) of human genes with at least two or more protein isoform sequences identified for each gene; the protein isoform sequences were then examined for the presence of Pfam/PRINTS signatures.
With the help of more REPAs in the genome, more diverse protein isoforms and functions of mammalian genes could be generated.
Only the translation initiation codon within exon I is characteristic of rodent BDNF genes, suggesting that there are more BDNF protein isoforms in human than in rodents.
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