Usually, a more comprehensive annotation generally annotates more genes and isoforms, and thus, increases the possibility of ambiguous mappings.
Consequently, IUTA can test many more genes differential isoform usage than can Cuffdiff2 for the same data.
The numbers indicate that some tissues include more genes with alternative isoforms than others (e.g. cerebellum).
Here, we provide a systematic analysis of the salm-regulated genes and gene isoforms in IFMs by mRNA-Seq and identify a core set of more than 700 fibrillar-specific gene isoforms, many of which code for sarcomeric components.
Compared to the number of differentially expressed genes at gene level, more genes showed differential expression at isoform level.
One reason that operonic genes have more transcript isoforms per gene than non-operonic genes do is that operons may contain a higher proportion of genes that generate multiple transcript isoforms.
However, over 90% of the genes identified in 3' gene expression profiling or whole transcript profiling were identified in exon profiling, along with 75%and38%8% more genes, respectively, showing evidence of differential isoform expression.
Comparing with other lincRNAs, hES lincRNAs generally had more complex transcript structure with longer transcript length (1,215 nt versus 906 nt, p-value < 2.2e-16), morexonsns per transcript (3.44 versus 3.00, p-value = 2.2e-06 2.2e-06re andernative isoformoreer gene (2.76 versus 1.42, p-valternative-16).
More isoforms of genes encoding α- amylase and β-amylase were expressed in parsnip and for β-amylase there was a difference in which isoforms were more highly expressed for sugar beet and parsnip respectively.
The statistics of different GO categories presume that DNA replication and chromosome cycle genes have more protein isoforms than the average.
