Sentence examples for more potent anticancer from inspiring English sources

Three compounds 9c, 9d and 11b showed 1.5 1.03 folds more potent anticancer activity than doxorubicin.

It was hypothesized that two-site binding would produce a more stable cleavage complex, and a more potent anticancer drug.

Among them, four compounds, 11f, 11g, 11i and 11j showed more potent anticancer activity than the control drug, Combretastatin – A4.

Compounds 6h and 6i exhibited more potent anticancer activity than 5-fluorouracil against the four tested human cancer cell lines and lower cytotoxicity to NIH3T3 normal cells.

Thus, deeper understanding the mechanisms of tumor angiogenesis and actions of these therapeutic molecules is crucial for designing more potent anticancer drugs.

These compounds could provide promising new lead derivatives for more potent anticancer drug development and delivery, and represent one of the most active classes of lapachones reported.

The authors of publications cited herein, while recognizing that only metformin is authorized by currently valid pharmacopeias for clinical use, note that phenformin, which is more associated with lactic acidosis in diabetic patients, may be more potent in anticancer applications, as follows from several preclinical studies [ 95, 96].

Therefore, compound 10 presents a good starting point for design of new, more potent and safer anticancer therapeutics.

Furthermore, compound 10m, was found to be about 2-folds more potent than the anticancer drug Sorafenib in hepatocellular carcinoma (HCC).

Collectively, these results strongly encourage further optimization of 15 as a new lead with multi-target properties to develop more potent compounds as anticancer agents.

Our findings indicate that coumarin 1,2,3-triazole coumarin 1,2,3-triazoleaffold for strucouldl optimization to develop more potent and selective anticancer agents and encourage further development of novel structurally related analogs of 33 as more effective 5-LO inhibetors.