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Although infection in humans with H5N1 remains rare, human cases continue to be reported and H5N1 is now considered endemic among poultry in parts of Asia and in Egypt, providing opportunities for additional human infections and for the acquisition of virus mutations that may lead to more efficient spread among humans and other mammalian species.

The 2 phenomena are not mutually exclusive and can be associated in the emergence and more efficient spread of resistance.

The dual-binding capability may indicate a wider range of cellular tropism and, therefore, more efficient spread of this virus in the respiratory tract.

In larger dairy herds there are more numerous between-animal contacts [ 8], increased inter- and intra-farm traffic by farm employees such as veterinarians and AI-technicians [ 8, 9, 16, 23] as well as potential higher animal densities [ 8] allowing the more efficient spread of infectious agents.

In summary, we suggest that the unusual evolutionary pattern of MtrA paralogs represents a novel example that gene conversion may help unsexual organisms escape from "Muller ratchet" (Muller 1964) by allowing for more efficient spread of beneficial mutations and removal of deleterious mutations after the convergent domain shuffling in different lineages.

Similar(55)

As environmental awareness increased through the 1960s and 1970s, gritting once again came under criticism due to its environmental impact, leading to the development of alternative de-icing chemicals and more efficient spreading systems.

Training also becomes more efficient when spread across a large workforce.

We therefore engineered MV-eGFP for IFN evasion and more efficient intratumoral spread by arming it with the P gene from wild-type IC-B strain MV, thus generating MV-eGFP-Pwt.

Their results support the hypothesis that a distributed practice may be more efficient when spread over several days instead of completed within one day.

So it could be that local increases in mistletoe are closely connected with the arrival of wintering blackcaps which are more efficient at spreading the plant's seeds.

"Warming boosts their rates of reproduction and the number of blood meals they take, prolongs their breeding season, and shortens the maturation period for the microbes they disperse" ― all of which makes them more efficient at spreading disease.

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