Sentence examples for more efficient knockdown from inspiring English sources

In addition, expression of shPHB1-3 resulted in a more efficient knockdown of both prohibitins.

However, as no difference was seen from the negative control in either condition despite apparently more efficient knockdown (Additional file 10), this was not pursued further.

For reasons that were not immediately clear, a slightly more efficient knockdown was achieved in tumor cells, as reflected by modestly reduced variability and lower overall mRNA levels.

Since microRNAs (miRNA -based gene silencing has miRNA -baseds-interference and more efficient knockdown effect (Chen et al., 2007; Haley et al., 2010; Ni et al., 2011), we employed this system.

In this present study, the partial knockdown of Nod1 resulted in decreased expression of duox, correlating with higher intracellular S. enterica burden when compared with the effects observed with the more efficient knockdown of Nod2 (Fig. 4C).

Interestingly, in EA.hy926 cell death was already significantly reduced upon knockdown of either Bim or Bid, most probably due to a more efficient knockdown of Bid and Bim compared to skHep-1 (Supplementary Figure 2).

Although higher concentrations of siRNA (>20nM) resulted in more efficient knockdowns, these were cytotoxic, and therefore for our studies we chose the least toxic concentration of PC-1 siRNA, which was 20 nM.

These results suggest that a more efficient SOX11 knockdown could lead to more rapid apoptosis when compared with cells with moderately reduced SOX11 levels, which may possibly undergo prolonged cell-cycle arrest before subsequent apoptosis.

Still, we observed more efficient shRNA knockdowns in the urothelial cell lines VMCub1 and SD than in the human T-cell line CEM.

Taken together, these results indicated that neither of the ch7SK-shEGFP constructs induced more efficient RNAi-knockdown of EGFP than existing cU6-shEGFP constructs in DF-1 cells.

Although both T1- and T2-knockdown protected cardiomyoblasts against damage during IAV infection, the protective effects of T2-knockdown were more efficient than those of T1-knockdown.