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Formate was a more effective substrate for promoting dehalogenation based on electron donor utilization efficiency.

However, the molecular details of Red recombination must be more clearly understood to enable more effective substrate designs for complex applications.

In vitro assays have shown that increased acetylation of the H3 tail domain directly causes increased H3K4 methylation by generating a more effective substrate for SET domain methyltransferases [18], [20].

According to this hypothesis the structurally altered amylopectin of the Atss2 mutants may provide a more effective substrate for GBSS, allowing greater levels of amylose production.

It seems that acetate was a much more effective substrate than propionate for selective enrichment of PHA producing cultures, leading to higher quantities of PHA stored.

While the rates of these reactions were noticeably less rapid than that of the fusion protein's natural counterpart, α2AP, it was clearly a more effective substrate than its synthetic peptide counterpart, α2AP(13-42).

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Interestingly, early observations suggested that dietary HPUFAs esterified to PLs rather than TAGs are more effective substrates for brain tissues accretion in term baboons [ 125].

To assess whether succinate semialdehyde and propionaldehyde are more effective substrates in the mutants than P5C/GSA is, the kcat/ Km ratio of wild-type BjPutA and each mutant [ kcat/ Km WT/ kcat/ Km mut] was determined for all the substrates.

One possibility is that binding to the mitochondria shields AF-6 ubiquitination sites or that parkin ligase activity at the mitochondria is diverted toward more effective substrates including a plethora of outer membrane mitochondrial proteins (48, 50, 51).

Also, as expected [ 1, 27, 28], [U-C]D-Man was a more effective biosynthetic substrate than [U-C]D-Glc.

Indeed, the similar concentration response of lactate and glucose on Vm indicates that lactate is a more effective energy substrate, on an energy basis, at closing KATP channels.

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