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Exact(5)
Increasing evidence supports gape size, rather than body size, as a more direct target for selection tracking diet shifts in insular snakes [26], [33].
There are clearly more direct target genes for Sox10 than those we have identified here.
It is quite possible that the abnormality of the mitochondria is also related to the actin cytoskeleton, a more direct target of PXN.
We develop here a similar method for satisfying equilibrium by using a target potential energy instead of the more direct target strain \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\hat{\lambda }$$\end{document }
Alternatively, it remains possible that there are more direct target genes, but the regulatory elements are more distal than ± 10 kb from TSS. ChIP-seq analysis provided a unique opportunity to begin to examine the molecular mechanisms by which PPARβ/δ differentially regulates gene expression.
Similar(55)
Therefore, targeting SOX2 in EGFR-mutant tumors may be therapeutically beneficial; however more direct targeting strategies need to be further developed.
Aggressive and invasive K-Ras-induced adenocarcinomas (IO33 and K-RasLA2) remained sensitive to more direct targeting of Foxp3+ cells through a neutralizing anti-CD25 antibody or genetic deletion.
Obviously, more comprehensive procedures such as ChIP-on-chip or ChIP-Seq screening would produce more direct targets.
It is desirable that future research should place more emphasis on specific areas of psychosocial disability in schizophrenia which could be more direct targets for interventions and policy changes.
Some believe Google could become a more direct legal target for Apple, especially as it moves further into producing its own hardware through Motorola Mobility and others, rather than simply making its Android operating system available to OEMs.
Given our data suggesting that gene activation and inflammatory repression by LXRs were mechanistically linked, we hypothesized that there must be one or more direct LXR target genes whose action has a secondary effect on inflammatory gene expression.
Related(20)
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Justyna Jupowicz-Kozak
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