Sentence examples for more direct targeting from inspiring English sources

Therefore, targeting SOX2 in EGFR-mutant tumors may be therapeutically beneficial; however more direct targeting strategies need to be further developed.

Aggressive and invasive K-Ras-induced adenocarcinomas (IO33 and K-RasLA2) remained sensitive to more direct targeting of Foxp3+ cells through a neutralizing anti-CD25 antibody or genetic deletion.

Increasing evidence supports gape size, rather than body size, as a more direct target for selection tracking diet shifts in insular snakes [26], [33].

There are clearly more direct target genes for Sox10 than those we have identified here.

Obviously, more comprehensive procedures such as ChIP-on-chip or ChIP-Seq screening would produce more direct targets.

It is quite possible that the abnormality of the mitochondria is also related to the actin cytoskeleton, a more direct target of PXN.

It is desirable that future research should place more emphasis on specific areas of psychosocial disability in schizophrenia which could be more direct targets for interventions and policy changes.

We develop here a similar method for satisfying equilibrium by using a target potential energy instead of the more direct target strain  \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\hat{\lambda }$$\end{document }

Alternatively, it remains possible that there are more direct target genes, but the regulatory elements are more distal than ± 10 kb from TSS. ChIP-seq analysis provided a unique opportunity to begin to examine the molecular mechanisms by which PPARβ/δ differentially regulates gene expression.

More complete studies are needed to determine the role of MRJ-L in macrophages, as well as more directed therapeutic targeting to specific cells to avoid potentially devastating off-target consequences.

Nevertheless, patients diagnosed with familial hypercholesterolemia seem to prefer a patient-mediated approach more than a direct targeting approach, as they consider it less threatening for relatives [ 17].