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Therefore, we elucidated the crystal structure of SaFBA to 2.1 Å allowing for a more direct structural analysis of SaFBA.
Techniques that are able to provide a more direct structural identification of the mineral content of rock art are increasingly being used in partnership with elemental analysis.
These data support a more direct structural role for QIL1 in MICOS stability.
Application of C H HSQC spectroscopy using selectively [C-ε methyl]methionine-labeled KSHV Pr allowed for more direct structural confirmation that compounds 2 and 3 disrupt dimerization.
Notably, we have shown that QIL1 does not affect cardiolipin levels or species distribution, supporting a more direct structural role for QIL1 in MICOS complex maturation.
This data supports a more direct structural role for QIL1 in MICOS stability, suggesting a scenario that would be more consistent with QIL1 being a component of the MICOS complex rather than being indirectly involved, for example, in promoting cardiolipin production.
Similar(54)
Other programs such as COILS (http://www.ch.embnet.org/software/COILS_form.html), and more importantly direct structural data for residues 6 166, indicate that the N-terminal part of Ndel1 forms a coiled-coil structure divided into three regions (Fig. 1B) (Derewenda et al., 2007).
The Monte Carlo method provides a more direct route to equilibrium structural and thermodynamic properties.
Given that β-stranded elements can be clearly ruled out by the 1D NMR data, we instead opted for a more direct comparison with the structural models.
Our results provide a more detailed and the first direct structural understanding of the COM domain interaction and will contribute to successful biocombinatorial engineering attempts in the design of artificial NRPS templates.
Metrics such as kurtosis, skewness, percentiles and their changes demonstrated to be strong and reliable quantitative surrogate markers of tumour heterogeneity with a more direct correlation to the underlying structural, physiological, molecular as well as metabolic changes occurring upon tumour progression with and without therapy.
Related(20)
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