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Our analyses also revealed that DpAV4a shared more core genes with CIV than with other ascoviruses and iridoviruses, providing additional evidence that DpAV4a represents a separate lineage.

This conclusion was supported by the finding that more core genes, 29, were shared by invertebrate iridoviruses and ascoviruses, or these viruses and DpAV4a, which shared 42, than with the vertebrate iridoviruses.

In contrast, strains from C2 shared relatively more core genes of most categories than those from the other two groups (Table 2).

Comparative genomics analyses of EcO145 with EcO55 and other EHEC strains reveals that EcO145 and EcO55 share nearly the same, or more, core genes than the number of core genes EcO145 share with other non-O157 EHEC strains.

In fact, although the B. anthracis genome (5311) contains many more genes than the Geobacillus kaustophilus genome (3498), B. anthracis has lost many more core genes than G. kaustophilus; this is partly due to the partial loss of the motility-related genes in the former genome (see Figure 2D).

Similar(55)

This implies that top pathways and pathway-based genes (leading edge genes) contained more core gene sets/pathways as stable biomarkers.

It has been noted that a mutation in one or more core clock genes is not sufficient to elicit increased tumor incidence in the absence of a cancer-sensitized genetic background.

Regarding core genome overlap, C. coli showed more unique core genes (86 vs. 35) as well as core genes in one species that are dispensable in the other (82 vs. 17).

A general feature of vertebrate gonadal sex-determining pathways is that master switches appear to have been added at the top of the hierarchy, with more conserved core genes appearing downstream.

We have also extended this study and have defined a more stringent core gene set compared to those previously published due to the comprehensive array coverage.

As a consequence of our comprehensive array coverage, we have also defined a more stringent core gene set compared to those previously published [ 30, 32].

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