Sentence examples for more key genes from inspiring English sources

We then hypothesized that one or more key genes responsible for RGA may be located in this chromosome region.

Genetic diseases are attributed to changes in the expression pattern of one or more key genes.

In order to identify more key genes involved in glucocorticoid-mediated regulation of BBB permeability, we used cDNA microarrays to study changes in gene expression in dexamethasone-treated brain capillary endothelial cEND cells: Primarily, we observed changes in expression of the VE-cadherin gene involved in cell adhesion.

We extended this annotation improvement to 7 more key detoxification genes families: 4 associated with phase I; 2 with phase II and 1 with phase III.

It is possible that one or more of the key genes have subtle sequence changes that render them inactive, but we have not observed any such mutations.

Compared with other plant genomes, apple has considerably more copies of key genes related to sorbitol metabolism.

For key genes more thorough interrogation requires exonic, intronic, and regulatory SNPs.

Subnetworks identified by Logit-Lapnet allow investigators to more readily focus on key genes for subsequent downstream functional analyses.

Since the first rare single-gene mutations were identified in severe early-onset obesity, far more common variants in key genes (and/or their promoter sequences) have been identified which explain significant weight variability within the population [ 5].

More recently, many of the key genes identified by genomic screening are T-cell related, including the MHC shared epitope association, PTPN22 and granzymes.

This suggests that more commonly, the regulation of key genes in these pathways plays a role in feedforward or feedback processes that then affect transcription rates of downstream target genes within the same pathway.