The evidence points to something more complex: genetic predispositions interact with circumstances to produce unique individuals.
But in most cases, autism is thought to have a more complex genetic origin, involving multiple genes acting together.
Now the mouse genome should help researchers develop a lot more models, especially for diseases with more complex genetic origins, like asthma, obesity, hypertension and diabetes.
But Recombine is hoping to take this a step further by looking for more complex genetic disorders.
Our results indicate substantial selective potential on these traits, but that the efficacy of selection for certain traits might depend on more complex genetic architecture.
Most metabolic engineering investigations have been made using such typical model organisms as Synechocystis sp. and Synechococcus elongatus sp. as well as Aanabaena sp., whereas much more complex genetic engineering is required for algae [16].
Three months after his lab's first CRISPR report, Jaenisch and co-workers published a second paper in Cell that suggested CRISPR could easily perform more complex genetic surgery, knocking in chunks of DNA rather than simply disabling genes.
For flowering time, we find that individual crosses often reveal a simple genetic basis, but that the loci involved almost always vary within species and across environments, indicating a more complex genetic basis species-wide.
If more complex genetic scenarios are considered, the accumulation of incompatibilities is even faster.
Such strains would potentially allow for more complex genetic analysis when used in combination with Cre and FLP expressing mouse strains.
The new data indicates that these genes are differentially expressed and subjected to a more complex genetic regulation than previously thought.
