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Exact(6)
Step-cooling gave a more complete depletion of the aluminum solid solution, i.e. lower flow stress, without forming coarse and stable Mg2Si particles which are very difficult to solutionize during reheating and thus survive the extrusion process impairing both surface quality and mechanical properties.
We cannot rule out the possibility therefore that a more complete depletion of ACh might have resulted in behavioral impairments.
Recently, a more complete depletion of synovial B cells by rituximab was demonstrated at a later time point following treatment [ 32]; however, this could be explained by an overall reduction of synovitis leading to a secondary effect on lymphocyte accumulation.
To explore this latter possibility, we pooled siRNA oligonucleotides targeting two Ska components simultaneously, in the hope that this would achieve a more complete depletion of the Ska complex than any 'single' knock-down.
The detailed role of B cells in RA remains to be elucidated because a more complete depletion of the peripheral CD20+ subpopulation following treatment with RIX was not consistently predictive for achieving or maintaining a clinical response in RA patients, suggesting that the timing of re- treatment should rather be based on disease activity than repletion of peripheral B cell levels [ 51].
Gaitanos et al further demonstrated that a more complete depletion of the Ska complex from HeLa cells, achieved by targeting multiple Ska complex components through RNAi, resulted in severe chromosome alignment defects, stemming from an inability to form stable kinetochore microtubule attachments.
Similar(54)
Therefore, it is possible that the synergistic effect arises because together cholinergic depletion of inferotemporal cortex combined with fornix transection produces a more complete cholinergic depletion throughout inferotemporal cortex and rhinal cortex.
Several of these (with, in one study, 95% of non-responders showing poor early peripheral blood B-cell depletion using a high sensitivity assay) 71 demonstrate that seropositive patients who fail to respond to a first course of rituximab may respond to a second course 23 24 36 66 70 71 (accompanied by more complete B-cell depletion).
Body's reserves of thiamine are only 30 50 mg, so any malnutrition condition lasting more than 3-4 weeks can cause complete depletion of the vitamin's stores [ 3].
However, the complete depletion of one or more essential nutrients usually results in spores formation from metabolically active vegetative cells and eventually iturin A production ceases [ 19].
Interestingly, a more complete removal of the Ska complex by concomitant depletion of Ska1 and Ska3 results in a chromosome congression failure followed by cell death.
Related(20)
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