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These optimized reagents allow for quantification of the number of receptors expressed on the cell surface and a more accurate quantitation of receptor occupancy.
These approaches were applied to the experimental data of Clinical Proteomic Tumor Analysis Consortium CPTACC) Verification Work Group Study 7 and show that the corrected measurements provide more accurate quantitation than the uncorrected data.
Thus, counting only the cells depleted of LTAg should result in much more accurate quantitation.
They also allow more accurate quantitation of parameters such as muscle mass and cross-sectional area than can be achieved in human studies.
We attribute this to more accurate quantitation and normalization of transcript abundances, owing to the use of spiked transcript controls, as well as the use of larger arrays.
Although the flow-injection-based MRM approach serves as a rapid way to prescreen for the presence of altered fatty acyls in yeast mutants, more accurate quantitation of certain lipid species, in particular PE and PC, requires well-resolved chromatography separation.
Similar(44)
Our objective was to develop and characterize a second-generation positron-emitting analogue for PET/CT imaging, 64Cu-NOTA-pertuzumab F ab' 2, to provide greater sensitivity, more accurate radiotracer quantitation and a lower radiation absorbed dose.
The general concepts and applications of stable istotope labeling (SIL -assisted approaches for improved global feature detection, tracer metabolization, more accurate comparative quantitation, and metabolite annotation have been summarized in several recent review articles.
Strikingly, our system allows for increased sensitivity in detecting UPR activation and more importantly, accurate quantitation of ER stress.
The cell cycle distribution and the fraction of apoptotic cells were gated differently and determined separately in order to more easily achieve accurate quantitation of each parameter.
Note that because the tumor-stroma distinction relies on measurement of similar peptides of differing sequence (with accompanying mass differences), it is impossible to use more accurate mass spectrometric quantitation approaches that incorporate isotopic labels.
Related(20)
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