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Previously, we developed a software tool (DOVIS) to perform large-scale virtual screening of small molecules in parallel on Linux clusters, using AutoDock 3.05 as the docking engine.
Furthermore, leukocytes usually employ two separate adhesion molecules in parallel to home to diseased tissues, and we recently quantified the advantages of a two-receptor display for the targeting of leukocyte mimetics (Eniola AO, Willcox PJ, Hammer DA.
In developing new antioxidants it will be useful to utilize endogenous processes to activate and recycle the molecules in parallel with the targeting of compounds to cells and organelles in ways that are not limited by the constraints that impair the distribution of endogenous antioxidants.
A complex of one molecule with another was assembled by disposing the molecules in parallel, and the same procedure of energy-minimization was repeated to generate the final models: Alg-Gly, Alg-Ba2+, and Alg-Gly-Ba2+.
Leukocyte CD11b and LFA-1 are central to leukocyte-endothelium adhesion, and we also recorded a similar significant fall in plasma soluble adhesion molecules in parallel with increased monocyte expression of these adhesion molecules [ 25].
Recently developed microbead technologies capable of sequencing hundreds of thousands of DNA molecules in parallel provide a way to obtain genomic information from these species for reasonable cost, and without any bacterial cloning step.
Similar(54)
Glycolysis is a 10-step pathway that converts a glucose molecule into 2 pyruvates with a net production of 2 ATP molecules and in parallel provides intermediates for anabolic pathways.
But with 1,000 polymerase molecules working in parallel, each behind its own hole, the machine would sequence 10,000 bases a second, or 36 million an hour.
After HAART initiation, proinflammatory cytokines and adhesion molecules decrease, in parallel with an initial increase in peripheral CD4+ lymphocytes [16 18].
Therefore, we calculated quality criteria based purely on the covered molecules and in parallel, we also computed the coverage.
The resulting data was plotted as the net score of the interactions against the staggering between two molecules arranged in parallel (Figure 5A).
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