Exact(1)
To capture a broad assessment of the molecular processes represented by the ∼2000 modulated genes, we utilised gene ontology (GO) analysis [34].
Similar(7)
We used Gene Ontology (GO) resources and tools available at AgBase [ 57] to identify the molecular functions and biological processes represented in differentially expressed proteins in our datasets.
The majority of the ESTs represented on the marmoset array assigned with a gene symbol (in total 1251) could be classified according to gene ontology based on biological function (1034) or molecular process (1106), representing a wide variety of different functional classes (Additional file 1).
Uncovering the molecular mechanisms that control these processes represents an important next step in this research.
For a phenotype, a logical definition follows the entity quality (EQ) model (Mabee et al., 2007): the entity is what is affected, and can be the whole cell, a population of cells, a part of a cell (corresponding to a GO cellular component) or an event such as a molecular function or biological process (represented by GO terms).
Given the demonstrated link between network centrality and functional importance, these proteins are expected to have pervasive effects on a range of downstream molecular processes, and thus represent potential gatekeepers in the link between vitamin intake and disease.
Each of these processes represents the net result of numerous molecular functions and may be possible targets for therapeutic intervention.
These structural changes are associated with significant increases in sugar yield on enzymatic digestion, thus represent promising molecular processes for the utilization of bioenergy resources (Inouye et al. 2014).
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