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Using the BAgNP sol as substrate and based on the catalysis of Ti(IV) on the BrO3− oxidizing safranine T (ST) molecular probe with a strong SERS peak at 1,535 cm−1, a new catalytic SERS quantitative method was developed for the determination of 1.0 to 100 ng/mL Ti, with a detection limit of 0.4 ng/mL.
Development of molecular probe with combination of variable molecular marker is an attractive field which may enable detection of such a flat neoplasm much easier [ 42].
We demonstrated by a series of experiments that cy-apt 20 was an excellent molecular probe with a certain degree of biostability and high specificity and sensitivity for molecular recognition and targeting therapy of gastric cancer.
A molecular probe with high affinity to tubulin associated unit (TAU) fibrils and a low affinity for synthetic amyloid-β1-42 fisrins is in the early phase of development [ 93].
Our study demonstrated that cy-apt 20 was an excellent molecular probe with high specificity and sensitivity and a certain degree of biostability for molecular recognition and targeting therapy of gastric cancer.
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This directed approach yielded molecular probes with tuned dual activity.
These results demonstrate that the 2-thioxo-4-thiazolidinones can be considered as new promising molecular probes with excellent binding activities to PPARγ.
The purpose of this study is to develop molecular probes with appropriate NMR characteristics and the biocompatibility for in vivo applications using 19F MRI.
The nanotube can also be used as molecular probes with its application in chemistry and biology by chemically modifying the nanotube tip through the attachment of functional groups [28].
However, employing reversible covalent warheads in drug design has given rise to covalent enzyme inhibitors that serve as powerful therapeutics, as well as molecular probes with exquisite target selectivity.
The results of this work establish that the wild-type protein forms smaller oligomers than previously believed, define the roles played by various structural domains in Hsp27 oligomerization, and provide improved molecular probes with better-defined properties for the design of future experiments.
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