Sentence examples for molecular principles underlying from inspiring English sources

Induced pluripotency is a promising avenue for disease modeling and therapy, but the molecular principles underlying this process, particularly in human cells, remain poorly understood due to donor-to-donor variability and intercellular heterogeneity.

The molecular principles underlying the organisation of the early secretory pathway are largely conserved between mammals and Drosophila, with the exception that in mammalian cells the Golgi stacks are linked into a single-copy organelle, forming the Golgi ribbon.

The molecular principles underlying this protection remain unresolved.

However, the molecular principles underlying this interdependence are not fully understood.

Oocytes are crucial cells for mammalian reproduction, yet the molecular principles underlying oocyte development are only partially understood.

Indeed, if the molecular principles underlying the secretory pathway are largely conserved between mammals and Drosophila, some differences exist (Kondylis and Rabouille, 2009).

This suggestion is confirmed by a general thermodynamic assessment, which provides a basis for using simplified models to study the design principles underlying the molecular evolution of K+ channels.

It is of particular interest to apply the same design principles underlying naturally occurring molecular clocks, where rythmicity is mainly based on negative feedback loops [ 12], to the in vivo engineering of synthetic oscillatory circuits [ 13, 14].

This study is a first step towards using statistical characterization in determining the design principles underlying organization of complex molecular networks.

The principles underlying metal oxide phase formation from multicomponent molecular gels are reviewed.

The next generation of disease specialists needs to be acquainted not only with the power of molecular technology but also equipped to understand disease pathogenesis and the basic principles underlying disease control.