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Exact(5)

Furthermore, the late dysplastic cells exhibited activation of ESC-Core and ESC-Myc modules, indicating that acquisition of the transcription network of pluripotent stem cells is associated with the tumor development.

However, the identification rates of the two DCM-related modules were much higher than any other modules, indicating that these two identified modules were robustly related to DCM.

However, several representatives of DUF4145 are fused to restriction endonuclease (REase) and superfamily-II helicase modules, indicating that HEPN domains also commonly occur independently of MNTs.

QTL mapping showed clustering of volatile QTL included in the same volatile modules, indicating that some are subjected to joint genetic control.

Note that the majority of genes (74%, 34/46) in these modules had H3K27me3 enrichment within 1 kb of their transcriptional start site, versus only 7% (381/5566) of genes across all modules, indicating that most of these dysregulated genes are likely direct targets of EZH2.

Similar(55)

The mean MM ± SEM ranged from 0.60 ± 0.01 (brown module) to 0.74 ± 0.01 (tan module), indicating that modules consisted of genes sharing highly similar expression patterns.

All the relationships among modules indicate that each module has some regulatory impact on its follow-up modules, according to the peaks each module stands for.

The functional annotations enriched in each modules indicated that they are clearly functionally related to specific developmental stages.

Hence, the large fraction of significant modules indicates that our division into modules based on common motifs and co-expression is indeed relevant.

The retrieved modules indicate that CFinder has identified 2333 modules (named as "communities"), which are mostly based on 3- and 4- cliques (k = 3 - 355; k = 4 - 200).

Furthermore enrichments analysis for cell components modules indicates that the robust gene are strongly enriched in the intracellular (GO: 0005622) and ribosome (GO: 0005840), but the sensitive genes didn't show enrichment in the cell components.

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