Sentence examples for modulator of molecular from inspiring English sources

We propose that USF1 is an important modulator of molecular and behavioral circadian rhythms in mammals.

Taken together, these results show that USF1 is a significant modulator of molecular and behavioral circadian rhythms in mammals.

Thus, PINK1 seems to act as an upstream modulator of both molecular and organellar quality control pathways via HtrA2 and Parkin, respectively.

Our findings also support the hypothesis that PS2 (via its function as a γ-secretase) is a molecular modulator of microglia activation by acting as a repressor of proinflammatory responses.

Taken together these studies support the hypothesis that microglial PS2 functions in a manner distinct from PS1 to downregulate proinflammatory cytokine release and thus may act as a novel molecular modulator of microglia behavior.

These results suggest that InCell SMART-i will be useful for identifying targets of small-molecule modulators from phenotypic screening for development of molecular probes by biochemical approaches.[ 1, 12] In summary, we have developed a novel and effective readout for specific molecular interactions inside living cells by monitoring the induced assembly of nanoclusters.

In this study we have identified SU6668 as a small molecular weight modulator of Gli protein activity and shown that there are common elements in regulation of Gli1/2 transcriptional activators by TGF-β and Shh.

This signalling pathway has been identified as a modulator of cell-cycle progression through molecular events by which RhoA/ROCK/LIMK (LIM domain kinase) inhibition led to stress fibre disassembly, a decrease in ERK1/2 (extracellular-signal-regulated kinase 1/2) phosphorylation and subsequent cyclin D inhibition (Walker and Assoian, 2005).