Sentence examples for modulation of translation from inspiring English sources

It has been proposed that modulation of translation elongation rates along an mRNA might serve to fine tune the co-translational folding of the nascent polypeptide chain, ensuring its high accuracy and efficiency [ 115, 124].

Functionally, amyloids are involved in numerous physiological processes such as information transfer in neurons, melanosome biogenesis or modulation of translation termination [4].

An aminoglycoside family of antibiotics (e.g., gentamicin) was recently reported to partially correct the effect of nonsense mutations by specifically recognizing ribosomes and by promoting a readthrough mechanism for the modulation of translation and miscoding [5].

Extensive research has delineated transcriptional control pathways during myelopoiesis that are disrupted in leukemia and more recent investigations have highlighted differentiation-specific or leukemia-related posttranscriptional modulation of translation by microRNAs.

A concept that has gained more traction focuses on the idea that the modulation of translation and protein folding may help to further improve host cells [ 16].

Increasing amount of evidence is accumulating on co-translational processes and on the involvement of ribosome-bound chaperones in these events, including the assembly of ribosomes, modulation of translation and targeting of proteins.

Also GO-terms involved in translation regulation seem to be affected e.g. "regulation of translation" (GO 0006417), "translation regulator activity" (GO 0045182) and "translation factor activity, nucleic acid binding" (GO 0008135), implying modulation of translational activity as a response to desiccation.

This shows that SSA will increase our ability to tune multi-gene pathways at all control levels for the biotechnological production of complex metabolites, achievable through the combinatorial modulation of transcription, translation and enzyme activity.

In Aplysia, neurotransmitter modulation of local translation of mRNA in sensory afferents leads to long-term changes in synaptic efficacy [4], [5].

Multiple miRNA target sites within a 3'-UTR suggest that miRNAs act together to orchestrate the modulation of mRNA translation [17], [18], [19], [20], [21].

Type I circuits, in which the miRNA and its target are regulated together would allow for modulation of protein translation, maintenance of cellular homeostasis, or modulation of changes in local protein concentrations.