Sentence examples for modulating the transition from inspiring English sources

There is a wide array of natural and synthetic agents that hold promise for inhibiting, reversing, or modulating the transition from normal to precancer and from precancer to cancer.

Streptococcus mutans, a member of the oral microbial community, plays a key role in modulating the transition from non-pathogenic form to highly cariogenic biofilms [3], although additional organisms may be also associated with this ubiquitous disease (as reviewed in [4]).

These experiments highlight the interdependence of residues at positions 7.53 and 7.60 in modulating the transition to the active state.

Age-dependent changes in the concentration of miRNA modulating the transition from a crotoxin-rich to a SVMP-rich venom from birth through adulthood can potentially explain what is observed in the age-dependent proteomic analysis of the ontogenetic changes in the venom composition of C. s. simus illustrated in Figure  1.

These results support the view that age-dependent changes in the concentration of miRNA modulating the transition from a crotoxin-rich to a SVMP-rich venom from birth through adulhood can potentially explain what is observed in the proteomic analysis of the ontogenetic changes in the venom composition of C. s. simus.

Biophysical characterization of rare gain-of-function mutations affecting pain signalling has provided us with invaluable insight into the way various sodium channel blocking drugs differentially modulate the transition between the states of VGSCs.

Little is known about the factors that modulate the transition from one phase in the life cycle to the next, or about the changes in gene expression that occur during these transitions.

Since chloroquine inhibits lysosomal proteolysis and can theoretically also modulate the transition of lysosomal Cbl to the base-off state (as explained above), we also conducted the similar experiments using another proteolysis inhibitor that does not alter lysosomal pH.

DOI: http://dx.doi.org/10.7554/eLife.00971.016 Taken together, we have shown that the rate of entering the 1-bp backtracked state is higher than those of entering further backtracked states, and that the E1103G mutation modulates the transition kinetics between the 1-bp backtracked state and the pre-translocated state.

Therefore, the increased level of hnRNP K in the NM could be the critical step towards the activation of the numerous pathways involved in carcinogenesis, which are potentially regulated by hnRNP K. HnRNP K could directly or indirectly, through modifications of protein/protein or RNA complexes, modulate the transition from an open to a condensed chromatin state.

In summary, we have uncovered a dual regulatory role of Anxa6, one that regulates Parp1 activation and subsequent cell death machineries and the other as an enhancer of tubular mitochondrial morphology in hypertrophied cardiomyocytes, thereby acting as a molecular switch that modulates the transition of hypertrophic phase to apoptosis.