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To address whether PTK6 plays a critical role in modulating the survival of cells in the luminal space, we examined the effects of PTK6 downregulation on IGF-1-induced acinar formation and luminal filling.
These factors may play important direct or indirect roles in modulating the survival, invasion, and adhesion of disseminated tumor cells.
Erythropoietin is a glycoprotein that regulates RBC production by modulating the survival and proliferation of erythroid colony-forming units in the bone marrow.
Here we investigated, using in vitro and in vivo strategies, the role of galectin-1 (Gal-1), an evolutionarily conserved glycan-binding protein, in modulating the survival of human and mouse enterocytes.
In the present study we provide the first evidence showing a role for Gal-1 in modulating the survival of human and mouse enterocytes isolated from the small bowel; this mechanism could influence the maturation process of these cells during their migration from the crypt to the tip of the villus.
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Since indole has been reported to modulate the survival of E. coli persister cells (Vega et al. 2012; Hu et al. 2015; Kwan et al. 2015), we investigated the abilities of indole and 35 commercially available indole derivatives at a concentration of 2.0 mM to reduce the survival of E. coli K-12 BW25113 persister cells.
These results demonstrate a novel mechanism by which components of the innate immune system can modulate the survival of epithelial cells during inflammation and infection.
Moreover, olfactory enrichment or deprivation do not selectively modulate the survival of specific PGC phenotypes, supporting the idea that the integration rate of distinct PGC subtypes is independent from olfactory experience.
We conclude that the relBE2Spn operon seems to be activated when protein synthesis is inhibited, so that under these unfavourable conditions this TAS could contribute to modulate the survival response through stasis.
The production of BAFF by nonhaematopoietic cells might provide local niches to modulate the survival and function of B cells.
As a negative regulator of BAFF and CD40, the adaptor molecule Act 1 (Acruciallyially modulates the survival of all B cells [ 114].
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