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These results demonstrated that shikonin modulated activation of NF-κB through EGFR signalling pathway.
In Cowan's model, digit span involves the attentionally modulated activation of multiple long-term representations of numbers.
Thus, despite many similarities in their oncogenic capacity the different mutant forms and overexpression of Kras may lead to a modulated activation of downstream targets that are responsible for these distinct oncogenic capacities.
A competing model, first proposed by Cowan (1999), does not specify a dedicated storage buffer, but portrays short-term memory as an attentionally modulated activation of existing long-term representations of to-be-remembered items (Chen and Cowan, 2009).
The environment, ambient temperature, nutrition (11), or drugs (20) only transiently modulated activation of the BAP, whereas the initial development of brite cells at 21 days of age was independent of environmental factors.
We found the serotonin transporter gene SNP rs16965628 significantly modulated activation of the ventrolateral PFC in the PTSD group, but not the non-PTSD group (see Figure 3).
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NOX-modulated alterations in activation of redox-sensitive signalling pathways that are involved in the vascular remodelling characteristic of chronic hypertension are also important [ 10].
In the time window after the participants saw the final outcome position of the wheel of fortune, preference-modulated activations were found in the caudate nucleus, precuneus, lingual gyrus, cerebellum, and, to a lesser extent, in the pallidum.
High tumour cell proliferation involves increased oxygen consumption, leading to oxygen deficiency and hypoxia-modulated gene expression, including activation of vascular endothelial growth factor and CA9 gene transcription by Hif-1 α (Forsythe et al, 1996; Jiang et al, 1997; Maxwell et al, 1997; Carmeliet et al, 1998).
The acute behavioral responses brought about by the activation of neurotransmission-modulated humoral responses by psychological and physical trauma represent evolutionary adaptive responses critical for survival in an uncertain and potentially dangerous environment.
Likewise, the phosphorylation of NF- κB and activation of PI3K/AKT signaling modulated by FAK disable the tumor necrosis factor- α- (TNF- α-) induced apoptosis [ 29].
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