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Furthermore, numerous factors contribute to modulate the role of endocannabinoids on anxiety, such as genetic background, age, sex and situational context.

One possibility is that differential phosphorylation events can modulate the role it plays in a cell by altering its affinity for DNA or binding partners, such as c-Jun.

These differences may modulate the role of K-1 in different cell types leading to cell-specific effects.

Comprehensive analyses identified amino acid residues at E2-60 and E2-211 that modulate the role of the E1-A226V muthaton that first arose during the Indian Ocean epidemic [2], [5] on CHIKV infectivity in these vectors.

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Finally, we show that other common gamma-chain (γc) cytokines differentially modulate the roles of Mcl-1.

Ethylene modulates the role of NPR1 in the SA JA pathways crosstalk (Leon-Reyes et al. 2009).

Altogether, these results reveal that CXCR2-dependent senescence modulates the role of hPTTG1 overexpression in tumor growth and metastasis.

The role of LRG1 is not fully understood, although it is of interest due to its role in angiogenesis; where it acts as a pro-angiogenic factor modulating the role of TGF-β (Wang et al., 2013).

A description of the genes and signaling pathways modulating the roles of OPNc in these tumor models might improve understanding of its tumor-specific properties.

In addition, with the advent of fluid surfaces whose spatial patterns can be modulated, the roles of local and global adhesive patterning at cell cell junctions can now be explored.

Further, how different trophic cytokines modulate the specific role(s) of Mcl-1 is unknown.

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