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Local drug metabolism, the action of transporters, the rate of absorption, and receptor binding, modulate the duration of local action.
Cascades have also been considered to modulate the duration and timing of signals, filter noise, and otherwise regulate cellular decisions [6] [8].
We concluded that our data describe an antennal grooming circuit whose components have the potential to modulate the duration of grooming, possibly mediated by their connectivity.
Some breast imaging units use one or more tumour-related risk factors for local recurrence to modulate the duration and frequency of examinations [ 51].
Many tumour-related risk factors for local recurrence have been identified which could be used to modulate the duration and frequency of mammographic follow-up.
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Although BK stimulates the release of nitric oxide from the vascular endothelium, the released nitric oxide and its ability to stimulate guanylate cyclase only modulates the duration of, rather than the magnitude of, BK-induced coronary vasodilation.
Although both elephants employed the strategy, one was clearly better at it, modulating the duration of her blows to bring objects where she wanted them, the researchers reported 5 November in Animal Cognition.
The data support the conclusions that the coronary vasodilator response of the rat to BK is CYP-1A and KCa-channel mediated, that coreleased nitric oxide only modulates the duration of BK-induced vasodilation, and that these mechanisms are unaffected by moderate diabetes.
Finally, the combination of this experimental approach and simulations using single cells uncovers a new role for the M-current in modulating the duration of bursts of hyper-excitable activity.
We observe that acquisition of clinical immunity modulates the duration of infections, which in turn is responsible for the identification of transmission regimes where stable endemic equilibria coexist with stable disease-free solutions.
In order to assess whether the exposure time to a salient anticipatory cue that predicts a painful stimulus during active engagement in an attentional task drives amygdala activation irrespective of the degree of effortful engagement (i.e., RT), we parametrically modulated the duration of each trial (i.e., arrow).
Related(20)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com