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Modular tissue engineering was initially introduced as a method of building intrinsically vascularized tissue engineered constructs by mixing together smaller building blocks ("modules"), with each module designed to include both vascular cells as well as functional cells.
Modular tissue engineering is featured as an example.
Modular tissue engineering (TE) is a promising alternative to overcome the limits in traditional TE.
A modular tissue engineering approach may have advantages over current therapies in providing rapid and sustained revascularization of ischemic tissue.
Modular tissue engineering is a novel approach to creating scalable, self-assembling, three-dimensional tissue constructs with inherent vascularization.
The goal here was to demonstrate the advantages of modular tissue engineering as a 3D cell culture system.
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In theory, modular tissue-engineered constructs are an attractive option for 3D cell culture.
PEG microspheres produced by these methods with controlled sizes and densities may be useful for the production of modular scaffolds for tissue engineering.
By widening the scope of the currently available methods with a simple technique, we hope to encourage use of the modular approach in applications outside of tissue engineering, and to provide a simple tool for biological investigations of the behavior of cells in 3D at high density.
This study demonstrated that modular fabrication is a viable technique for creating large-scale engineered cartilage, which can be broadly applied to many tissue engineering applications and construct geometries.
Furthermore, the modular hydrogel composition allows tailoring of mechanical and physical properties for specific tissue engineering applications.
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