Sentence examples for modular pathway engineering from inspiring English sources

These results suggest that modular pathway engineering can systematically optimize biosynthesis pathways to enable an efficient production of fumarate.

In our previous work, a recombinant Bacillus subtilis strain for the microbial production of N-acetylglucosamine (GlcNAc) was constructed through modular pathway engineering.

Engineering cell factories for producing biofuels and pharmaceuticals has spurred great interests to develop rapid and efficient synthetic biology tools customized for modular pathway engineering.

This work significantly enhanced GlcNAc production through modular pathway engineering of B. subtilis, and the engineering strategies used herein may be useful for the construction of versatile B. subtilis cell factories for the production of other industrially important chemicals.

Recent studies in synthetic biology showed that modular pathway engineering could be successfully applied to develop and optimize artificial biological systems [ 12– 12].

The multivariate modular pathway engineering was composed of two modules separated at the level of isopentenyl pyrophosphate (IPP /dimethylallyl pyrophosphate (DMAPP).

This review focuses on two practices that increase the likelihood of finding a more advantageous pathway solution: implementing a screen to identify high producers and utilizing modular pathway design to streamline engineering efforts.

To facilitate combinatorial pathway engineering and facile genetic operation, we engineered a set of modular cloning vectors compatible with BioBrick standards, called YaliBricks, to allow for rapid assembly of multigene pathways with customized genetic control elements (promoters, intronic sequences and terminators) in the oleaginous yeast Yarrowia lipolytica.

Here, we report that such precursor pathway engineering also dramatically increases yield (up to >1,000-fold >1,000-foldtext of our modular system, whinh provides a means for itheuse in de novo investigation of novel enzymaticontextity and hence, cofrespouring modularic pathwaysystem

Pathway engineering to combine established substrate-utilization programs, such as for cellulose, CO2/H2 or CO, with desirable metabolic programs could lead to modular design of strains suitable for many applications.

After pathway engineering, genome replication engineering assisted continuous evolution was applied to improve methanol utilization.