Nanoarrays, which consist of probe biomolecules immobilized on a chemically modified surface, have attracted much attention for the development of nanobiosensors.
The modified surfaces have different hardness, corrosion and wear properties.
The performances of various materials modified surfaces have been discussed with special emphasis on their cellular adhesion and electrochemical measurements.
Changes in wettability and the electrochemical stability of the modified surfaces have been also analyzed.
It has been shown that the temperature-responsive behaviour, originally presented by the biopolymer, is present in the modified surfaces having HAP as the outermost layer.
Choline phosphate (CP) containing polymers modified surfaces have been shown good resist to the adhesion of proteins while prompt the attaching of mammalian cells due to the dipole pairing between the CP groups of the polymer and the phosphorylcholine (PC) groups on the cell membrane.
With these promising features, self-assembling peptide modified surfaces have great potential for use in (bio molecular sensing and tissue engineering.
