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Table 1 Examples of modifications to modulate antibody effector function.
We postulate possibilities to utilize biomaterial physicochemical modifications to modulate the host inflammatory response and develop strategies for effective biomaterial integration.
Taken together, histone H3 phosphorylation acts in concert with other histone modifications to modulate essential cellular processes via at least two different mechanisms.
ISWI complexes are recruited to their nucleosomal substrates through their interactions with DNA-binding domains with the extranucleosomal DNA and/or by recognizing histone modifications to modulate chromatin structure [ 43, 44].
The ability of post-translational modifications to modulate the aggregation propensity of peptides and proteins in vivo is important in the progression of a range of amyloid related diseases.
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The authors noted that modification of the end group of the polymer used to form the nanoparticles altered the size and positive ζ-potential of the nanoparticles with a resultant impact on transfection efficiency and, critically, the potential for cell-specific polymer modification to modulate transfection efficiency in undifferentiated hESCs compared to human umbilical vein cord cells.
Most, if not all, parasite antigens utilize the change of surface post-translational modifications (PTM) to modulate and possibly evade the host immune response.
This post-translational modification appears to modulate MeCP2 binding at the BDNF promoter in the hippocampus.
Posttranslational protein modifications are known to modulate key biological processes like proliferation and apoptosis.
Presently, one focus is the rare-earth modification of Y to modulate its acidity and cracking activity.
Changes in DNA methylation and histone modifications have been shown to modulate the expression of several genes in pulmonary fibrosis; however, this is the first demonstration of histone modifications being responsible for the specific downregulation of Fas and the resistance of fibrotic lung fibroblasts to Fas-mediated apoptosis.
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modifications to regulate
changes to modulate
modifications to alter
modifications to adapt
modifications to influence
changed to modulate
modifications to tailor
change to modulate
modifications to generate
modifications to fit
modifications to bypass
modifications to stabilize
modifications to support
modifications to serve
modifications to unclog
modifications to be
modifications to improve
modifications to decrease
modifications to meet
modifications to enable
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