Sentence examples for modifications and mutations from inspiring English sources

We updated PatternLab to take advantage of the new Comet-PEFF search engine that enables identifying post-translational modifications and mutations included in neXtProt's PSI Extended FASTA Format (PEFF) metadata.

Our study also provides a structural basis for further investigation of dynamic regulation of PKM2 by other post-translational modifications and mutations involved in cancer metabolism.

However, an antibody approach is not ideal to detect and to quantify protein modifications and mutations but there is hope that MS might elucidate how best to proceed.

Our study reveals the mechanism for dynamic regulation of PKM2 by post-translational modifications and a patient-derived mutation and provides a structural basis for further investigation of other modifications and mutations of PKM2 yet to be discovered.

The differences between the obtained sequences the authors interchangeably call "polymorphisms", "substitutions", "modifications" and "mutations".

We previously reported detailed NMR characterization of transient HG bps in A6-DNA as well as variants that bear chemical modifications and mutations at the same position.

In addition to gene expression profiling, epigenetic data, including DNA methylation and histone modifications, and mutation analysis in cancer have been studied comprehensively in a genome-wide manner.

In addition to profiling gene expression, RNA-seq has shown powerful applications in areas, such as cataloguing of non-coding RNAs, investigation of the transcriptional structure of genes and splicing patterns, and the study of posttranscriptional modification and mutations [ 12].

We have made the first attempt to use low-energy ions in plasma immersion ion implantation and deposition (PIII-D) to bombard naked plasmid DNA to investigate effect on the DNA structural modification and mutation.

Mechanisms involved include modification of the drugs to less toxic derivatives or avoidance of their action by exclusion, target modification, and mutation of target-associated genes.

Phosphorylation at Ser112 is a major post-translational modification, and mutation at the site alters transcriptional and adipogenic activity of PPAR γ.