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These effects are presumably due to changes in the relative rates of transcription, translation, enzymatic modifications, and degradation.
Both the DNA plasmid and viral components of our vaccine are based on parasite DNA sequences which the mammalian cell uses to produce antigenic proteins using its intrinsic controls for folding, post-translational modifications, and degradation.
These processes are regulated by transcription, translation, post-translational modifications and degradation of key regulatory proteins, and as such, the ubiquitin proteasome system has a crucial role in maintaining and regulating cellular homeostasis [7].
Second, we found co-expressed modules that strongly correlated with re-organization of the secondary cell walls and with modifications and degradation of hemicellulosic structures.
In addition to full-length protein, many different forms of APC are known to exist within a cell as a result of alternative splicing, post-translational modifications and degradation (reviewed by Polakis, 1997).
The usage of FFPE tumors is advantageous because of the large amount of routinely stored tumors, but gene expression analysis of this material has been challenging because of chemical modifications and degradation of the RNA [ 26].
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As one of the post-translational modifications and degradations that occur during biopharmaceutical protein production processing and storage, cross-links have been reported to result in aggregation, loss of bioactivity, and immunogenicity.
The chemical modification and degradation of the organic layer was followed by XPS analysis.
Purple rectangles represent differentially expressed genes involved in hormone signaling; cell wall synthesis, modification and degradation; proteolysis and transcription factors.
Purple rectangles represent differentially expressed genes involved in hormone signaling; proteolysis; cell wall synthesis, modification and degradation.
SubBINs shown by yellow, red and blue rectangle represent differentially expressed genes involved in hormone signaling; protein modification and degradation; and receptor kinase activity, respectively.
Related(13)
changes and degradation
corrections and degradation
change and degradation
alteration and degradation
modifications and payment
modifications and refurbishing
modifications and parameter
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modifications and weight
modifications and community
modifications and process
modifications and refinancing
modification and degradation
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