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Further synthetic modification was undertaken to optimize the potency of amide compounds.
Structural modification was undertaken to separate CCR4 antagonism from the cytotoxicity of the compounds by varying the central aromatic core and terminal aromatic moiety.
This modification was undertaken to avoid narrowing of the prerectal space.
Bisulfite modification was undertaken using the EpiTect Bisulfite Kit following manufacturer's instructions (QIAGEN, Crawley, UK).
This modification was undertaken based on the work of our colleague and collaborator, Dr. JP Clancy et al., on adenosine regulation of CFTR [ 50, 51].
Similar(55)
There were complaints by the end users regarding the performance, hence modifications were undertaken.
There were complaints by the end users regarding the performance, hence modifications were undertaken. .
This meant that the last of the S15 class was not completed until 1936, although weight-saving modifications were undertaken to this batch.
Dose modifications were undertaken according to the toxicity in the previous cycle.
Further follow-up scaffold modifications were undertaken to improve DMPK properties and achieve higher efficacy.
Decisions about initial design and subsequent modifications were undertaken by an experienced multidisciplinary team with input from laypersons and independent experts.
Related(20)
modification was conducted
alteration was undertaken
modification was initiated
adjustment was undertaken
modification was understood
change was undertaken
modification was implemented
modification was evaluated
changes was undertaken
modification was observed
modification was made
modification was assessed
modification was utilized
modification was shown
modification was required
modification was fixed
modification was verified
modification was performed
modification was accomplished
modification was allowed
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