Sentence examples for modification status in from inspiring English sources

To do this, we performed ChIP-qPCR experiments to analyze the chromatin modification status in the COX-2 promoter region.

Two lysine residues were both methylated and acetylated, with structural modelling implicating their modification status in differentially modulating key PABP1 protein interactions.

To investigate priming of HSPC-specific genes, we investigated their histone modification status in embryonic stem cells (ESCs) using published datasets [ 39].

Although several studies have examined the clinical relevance of E2F1 through assessment of message and protein levels of human tumor samples, there is a dearth of information regarding the post-translational modification status in clinical samples.

Analysis of Scl expression as well as chromatin modification status in wild-type (WT) and mutant cells suggested that post-transcriptional compensatory mechanisms contribute to the mild phenotype in addition to redundant regulatory elements within the locus.

Consistent with the observation made with data from CD4+ cells, SVM models based on genomic sequence features are generally able to predict the histone modification status in the same cell line, with an accuracy ranging from 65%to75%5% across 27 different data sets.

Therefore, the posttranslational modifications status in regulation of VHL E3 ligase activity remains understudied.

Conversely, in mouse Arg and Arg were methylated in the absence of PRMT4, consistent with the modification status observed in Figure 2(A).

Protein arrays have already been applied to study changed expression levels or post-translational modification status of proteins in cellular stress conditions or in normal and cancerous prostate and ovarian tissue.

Intercellular heterogeneity, i.e., differential DNA modification status between cells in a population, is a major cause of phenotypic heterogeneity in many organisms [76].

Moreover, a universal exclusion list approach should improve the capabilities of LC-MS/MS for the discovery-based characterization of dynamic changes in RNA modification status allowing this technique to be used in large-scale studies of the epitranscriptome.