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Epigenetic regulation includes a wide range of regulations at transcriptional or post-transcriptional levels, such as DNA methylation, histone modification, chromatin remodeling, and lncRNAs.
DNA methylation and hydroxymethylation, histone modification, chromatin remodeling, ncRNA.
Epigenetic inheritance occurs through four basic layers deeply interconnected: DNA methylation and hydroxymethylation, histone modification, chromatin remodeling, ncRNA.
The epigenetic events involved in initiation and progression of melanoma may be aberrant methylation of the promoter regions, histone modification, chromatin remodeling, and the positioning of nucleosomes.
Our study identified a high prevalence of somatic mutations in genes encoding epigenetic regulators, including those involved in DNA demethylation, histone modification, chromatin remodeling, and microRNA processing.
Genes encoding proteins involved in DNA methylation/demethylation, histone modification, chromatin remodeling, or processing of non-coding RNAs (such as microRNAs) were categorized as "epigenetic regulatory genes".
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Organisms are able to regulate genome activity in response to stress through specific gene-environment interactions mediated by epigenetic mechanisms, which include DNA methylation, histone modifications, chromatin remodeling activities, and action of various small noncoding RNAs.
The epigenome is the sum of all epigenetic information [ 11] and refers more precisely to the complete description of chemical changes to DNA and histones [ 12], including histone tail modifications, chromatin remodelling proteins, and ncRNA.
Chromatin can be regulated by epigenetic factors including DNA methylation, histone modifications, chromatin remodeling, regulation of noncoding RNAs, and higher order chromatin structure.
Epigenetic changes, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs, are significantly involved in colitis-associated cancer development and progression.
Besides post-translational modifications, chromatin remodeling is also involved in the target gene selectivity of p53 target genes.
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