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Interaction terms were created in order to account for effect modification between variables.
Effect modification between variables was evaluated.
Effect modification between variables was calculated by means of dummy variables as proposed by Rothman (27).
In addition to examining statistical significance and confounding, the effect modification between variables was evaluated by testing appropriate interaction terms for statistical significance.
We also assessed interactions (effect measure modification) between variables and included the relevant interaction terms in the initial multivariable models if they were statistically significant (P < 0.05) in univariate analysis.
Effect modification between variables was calculated by means of dummy variables, as proposed by Rothman [ 33], according to whom a synergistic effect is present when a dependent variable has a greater impact on an outcome in the presence of a third variable (i.e., the association becomes "more than additive").
Similar(54)
The multivariate model was built including all variables with a significant association in univariate analysis (p < 0.05) and those considered potentially clinically relevant; modification effects between variables were also studied.
Furthermore, we tested for effect modification between independent variables.
High BMI and cigarette smoking were independently associated with increased risk of pancreatic cancer and there was no apparent effect modification between these variables (P for interaction=0.74).
Effect modification was checked between variables in the model to identify significant interactions (P < 0.01).
Effect modification was checked between variables in the model to identify interactions that were significant at the level of P<0.01.
Related(11)
modification between factors
variation between variables
changes between variables
modification between sessions
modification between males
modification between parents
modification between cells
modification between genetics
modification between groups
modification between patients
modification between covariates
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