Sentence examples for modification and turnover from inspiring English sources

The central circadian pacemakers in the mammalian and fly brains involve cellular feedback loops regulated at the level of protein modification and turnover, transcription and translation, and can coordinate biological rhythms throughout the animal in response to stimuli such as heat and light [7], [8].

Finally the amounts of functional proteins are influenced by protein folding, posttranslational modification, and turnover [ 26, 27].

The intracellular signals that control matrix gene expression elicit their effects through regulation of gene transcription or through post-transcriptional modification and turnover of gene products (i.e. stability of mRNA).

Again, these results may evidence the expected heterogeneity of cell populations within our Early-meiosis tissue or, alternatively, a more complex interplay between transcription, histone modification and turnover, and chromatin accessibility for DSBs.

Possible targets are diverse, with genes related to the synthesis of secondary metabolites represented most strongly, in addition to genes involved in protein modification and turnover, or primary metabolism.

Hence, regulated mRNA stability is a major contributor to differential mRNA abundance, although regulated protein synthesis, modification and turnover are clearly major additional contributors to regulated gene expression [ 19, 20].

In our study, 4.27% of the CaUnigenes correspond to proteins involved in protein modifications and turnover.

Exploring the relationship between post-translational modifications and turnover, we found that turnover is significantly greater when a histone peptide becomes acetylated than when it is methylated.

The little correlation between mRNA and protein abundance has been well demonstrated due to the regulation of transcription and translation, mRNA processing, mRNA stability and degradation, and protein modifications and turnover [ 4].

Low yields of the recombinant protein product can be the result of limitations at every stage of gene expression, from transcription, through transcript processing and half-life, translation, post-translational modifications and turnover.

Other functional classes more moderately conserved between the two species include metabolism, protein modification, folding, and turnover, and defence/detoxification systems.