Sentence examples for models which recapitulate from inspiring English sources

This can only be achieved through the use of functional models which recapitulate all aspects of the human disease.

Here, by considering minimalist mathematical models, which recapitulate scaffold effects seen in more mechanistically detailed models, we obtain analytical and numerical results that provide insights into scaffold function.

Parkinson's disease (PD) is a common age-related neurodegenerative disease and it is critical to develop models which recapitulate the pathogenic process including the effect of the ageing process.

However, these studies have been performed mainly in in vitro or animal models, which recapitulate only some aspects of the pathophysiology of human Alzheimer's disease.

In addition, a high-fat diet inducing inflammation in K-Ras (G12D) mouse models, which recapitulate human PDAC, was shown to enhance tumor promotion.

A number of murine MB models have been created allowing comparative analyses (reviewed in [ 16]), including models which recapitulate WNT [ 4] and Group 3 [ 17, 18] tumours.

Good animal models for HIV and TB exist, but there is not a model which recapitulates HIV-infection in an individual with latent TB.

Therefore, we chose the well described HSE tissue model, which recapitulates human skin and wound healing, to test antibodies directed at β4.

We investigated the role of Rest in neural development using an in-vitro ES cell-derived neural differentiation model, which recapitulates events during neural development in vivo.

It is possible that the wd-NHBE cell model which recapitulates the morphological and physiological features of the human conducting airway in vivo would be a more representative model to study respiratory infection.

In summary, these results indicate that the layered rLSEC-PEM-hepatocyte model, which recapitulates key features of hepatic sinusoids, is a potentially powerful medium for obtaining comprehensive knowledge on liver metabolism, detoxification and signaling pathways in vitro.