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Combined with pharmacophore models, knowledge of the drug-binding site of hERG channels will facilitate in silico design efforts to discover drugs that are devoid of this rare, but potentially lethal, side-effect.
As a result, and in contrast to the vast amount of connectivity data available in animal models, knowledge of human brain connectivity remains relatively poor.
For gene regulatory models, knowledge of all pathways to achieve a specific event, such as bistable transition of lac operon in E. coli [ 13- 15], may be used to guide laboratory experiments.
In the logistic regression models, knowledge of the side effects was categorised into "yes" and "no" where "yes" category included all subjects who correctly knew side-effects of each of their medications.
Although information of the conductivity ratio of adjacent compartments may be sufficient in some models, knowledge of electrical conductivities are needed for finite element and combination MEG/EEG models (Law 1993; Haueisen et al. 1997).
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The control scheme and design are based on local state information and model knowledge of the adjacent subsystems.
To simulate such cyclic hardening material response during RCF using finite element (FE) modeling, knowledge of localized cyclic hardening properties of bearing steels is required.
In a multivariate model, knowledge of evolutionary terms was predicted by education and religious denomination.
We will model knowledge of LDKT as the dependent variable using multivariable linear regression models with GEE.
We validate the approach using two testbeds that model knowledge of the MTBC obtained from two different experts and large DNA fingerprint databases to predict MTBC genetic clades and sublineages.
In order to compare both bottleneck models, prior knowledge of the bottleneck timing is crucial to distinguish models that do and do not implement ancient gene flow.
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Justyna Jupowicz-Kozak
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