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Human cell culture models further support a mechanism in which YAP or TEAD over-expression leads to an increase in the proliferation capability of a cell [14, 49].
Data from other acute kidney injury models further support the role of TLRs in renal danger signaling [17], [18].
Studies in acute myeloid leukemia models further support this idea.
Parkin overexpression models further support the role of parkin in mitochondria.
Multiple in vivo MYC-overexpression cancer murine models further support MYC as a therapeutic target [ 44].
2) Because the current data do not convincingly rule out other models, further support for the model is needed by challenging the model with additional stepping stone constructs.
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The fact that MSCs are present only transiently at the site of injury in animal models further supports this hypothesis [8].
Familial Hemiplegic Migraine 1 (FHM1) and 2 (FHmutationsionsharere the ability to facilitate the induction and propagation of CSD in mouse models, further supporting the role of CSD as a key migraine trigger [13].
Evidence from in vivo models further supports this.
Additionally, including deep single targets improved our foraging models further supporting previous findings of beaked whale foraging behavior [6], [8].
Analysis of two mouse models further supported the idea that CpdA has potent anti-inflammatory activity but exerts only little side effects when applied in vivo.
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