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The fact that MSCs are present only transiently at the site of injury in animal models further supports this hypothesis [8].
Evidence from in vivo models further supports this.
Altogether, the extensive regulation of our gene signature at different developmental stages and in differentiating cortical neurons, as well as in several neurological mouse models further supports their importance for the proper functioning and development of the mouse brain.
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Human cell culture models further support a mechanism in which YAP or TEAD over-expression leads to an increase in the proliferation capability of a cell [14, 49].
Familial Hemiplegic Migraine 1 (FHM1) and 2 (FHmutationsionsharere the ability to facilitate the induction and propagation of CSD in mouse models, further supporting the role of CSD as a key migraine trigger [13].
Data from other acute kidney injury models further support the role of TLRs in renal danger signaling [17], [18].
Additionally, including deep single targets improved our foraging models further supporting previous findings of beaked whale foraging behavior [6], [8].
Analysis of two mouse models further supported the idea that CpdA has potent anti-inflammatory activity but exerts only little side effects when applied in vivo.
It also has anti-tumor activity in xenograft tumor models, further supporting the notion that suppressing glucose starvation mediated UPR could be a potential novel anticancer strategy.
Another hybrid model of PSSM, DPC and AAC (hybrid-8) was developed with which we were able to achieve an accuracy of 91.42%, similar to that of hybrid-4 and 5. Thus, the accuracy achieved by hybrid-6 and PSSM based model were the best amongst all the hybrids and standalone models, further supported by the highest MCC of these models.
Studies in acute myeloid leukemia models further support this idea.
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CEO of Professional Science Editing for Scientists @ prosciediting.com