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We successfully managed to establish a model with unilateral acute kidney injury seen as low urine production and GFR as well as increased apoptosis quantified with detection of caspase-3-active cell profiles in the kidneys subjected to ischemia.
In an established pig model with unilateral renal warm ischemia, we found significantly reduced 99mTc-sestamibi uptake relative to perfusion in the kidneys exposed to ischemia indicating a potential ability to detect renal ischemic and reperfusion injuries.
Accordingly, we studied the effects of increasing PEEP-levels on ventilation, lung perfusion, oxygenation, and hemodynamics in an animal model with unilateral lung injury.
In one rat model with unilateral nephrectomy, cisplatin combined with radiation led to alterations in urine osmolality and volume due to tubular damage, which was histopathologically evident [ 7].
The most common animal model used to date is a rat model with unilateral peripheral denervation of one hind limb combined with high levels of systemic corticosteroid administration [ 17, 18]; other models of disuse and muscle unloading are hind limb suspension, spaceflight, joint immobilization, and spinal cord isolation [ 19- 22].
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In contrast to this, for the mathematical models with unilateral boundary conditions of Signorini type, the contact area is not known a priori [7 14].
Hong et al. [12] investigated a single species model with intermittent unilateral diffusion in two patches.
A two degree-of-freedom dynamic model with one unilateral frictional contact is built for one of the friction driven structures.
The purpose of this report is to show the establishment of an animal model with a unilateral maxilla defect, application of virtual reality and rapid prototyping in the surgical planning for dentoalveolar distraction osteogenesis (DO).
The crack is modelled with a unilateral elastic bending-stiffness behaviour, represented by a unilateral rotational spring.
For this purpose, a general computer model for tensegrity assemblies with unilateral microfilaments and buckled microtubules is developed and applied to the theoretical analysis of the mechanical response of 2D and 3D examples of tensegrity cells mimicking the behavior of real living cells.
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