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First, a finite element model of stage II AAFD was established in which virtual surgery of subtalar arthroereisis was simulated.
The effect sizes for age, gender, NCI Comorbidity Index, and cardiovascular disease were larger in the model of Stage I-II patients than the model of Stage III-IV patients, whereas the effect size for year of diagnosis was larger in the model of Stage III-IV patients.
Moreover, in the African trypanosome, NMT is now pharmacologically validated with compounds such as DDD85646 that specifically inhibit the enzyme and are curative in the mouse model of stage one African sleeping sickness [ 13].
Its modest in vitro potency (IC50 around 1 μM) was offset by good pharmacokinetic properties giving 100% cure in a mouse model of stage 2 disease following a 25 mg/kg once a day for 7 days oral dosing.
The simulation model represents a computer code implementation of the platform model of Stage 1. Code development can be time‐consuming and require specific software engineering expertise; thus, to expedite matters an increasing number of toolkits and ABM‐specific software libraries have become available.
CPD-0802 at 20 mg/kg once datly, intraperitoneally, for 10 days cured the GVR35 CNS mouse model while a daily 5 mg/kg intramuscular injection for 5 days cured a vervet monkey model of stage 20(T. b. rhodesiense) disease.
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A mathematical model of stage-wise for retrofit HEN can include additional equations and limitations for retrofits.
A new mouse model of stage-specific bone growth failure and fracture has been recovered as an autosomal recessive mutation, designated spontaneous fracture (sfx).
A simple model of stage-hemisphere-interaction is presented and verified in order to identify design rules and adequate excitation regimes.
Table 1 offers a model of staging that includes cognition, function, and behavior.
Next, we used the quality model of Donabedian to develop a model of stages and essential aspects in the process of registration [ 23].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com