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The specimens of stage IV disease had the largest percentage of over-expression (87.5% versus 12.5%).
However, the difference of gene expression between high-stage and low-stage tumors was not statistically significant due to only two specimens of stage I tumors were deposited at this data base.
The Rab11 expression was higher in tumor tissues than in non-tumor tissues in 100 cases (88.5%), especially specimens of stage III tumors, which showed the largest percentage of over-expression of Rab11 (94.2% versus 5.8%).
We performed comprehensive protein analysis of 24 surgically resected specimens of stage I adenocarcinoma using liquid chromatography-tandem mass spectrometry (LC-MS/MS), followed by bioinformatical investigations to identify protein molecules.
Therefore, we attempted to identify biomarkers of either responders or nonresponders including relapse-free patients without PAC using uracil tegafur, for selection of patients who would benefit from PAC using proteomic analysis of surgically resected specimens of stage I lung adenocarcinoma.
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In addition, 141 specimens of Stages I III IDC were obtained from women who underwent surgical treatment in two different periods, 1995 1999 (n = 42) and 2007 2008 (n = 99), in the Department of Surgery, Tohoku University Hospital, Sendai, Japan.
This explains why K5 was not identified in our control specimens of plaque stage.
Melanoma cell lines were established from surgical specimens of AJCC stage III and IV melanoma patients.
Melanoma cell lines were established from surgical specimens of AJCC stage III and IV melanoma patients admitted to Fondazione IRCCS Istituto Nazionale dei Tumori, Milan [ 22, 23].
We collected specimens of 73 stage T1N0M0 and T2N0M0 oral squamous cell carcinomas of the tongue, as well as samples from normal oral mucosa, dysplastic lesions, and invasive carcinomas (n=39).
AQP 3 protein expression was investigated by immunohistochemistry in specimens of 87 stage T1 UBC patients, who were diagnosed by transurethral resection of the bladder (TURB) and subsequent second resection at a high-volume urological centre between 2002 and 2009.
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