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Therefore, this study aimed to characterize the dental pulp stem cells isolated from dog teeth (cDPSCs) in order to further define the dog as an animal model for regenerative endodontics.
As well, advances in induced pluripotent stem cell (iPSCs) technologies [ 6- 8] make the pig an attractive model for regenerative medicine and stem cell research.
The medusazoan model system, Hydra, has long been a comparative model for regenerative study, bridging the gap between early animals, planarians, flies and vertebrates.
Likewise, the maxillary sinus of rabbits is considered to be a good experimental model for regenerative studies following sinus surgery [ 27– 33].
These results suggest that the telencephalic VZ contributes to neural tissue recovery following telencephalic injury in the adult zebrafish, and that the adult zebrafish is a useful model for regenerative medicine.
So far, our results indicated that hPLAP-tg rats could serve as a very attractive model for regenerative therapies because of ubiquitous and strong expression of the transgene, and excellent preservation of the marker enzyme in paraffin and MMA sections.
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Dogs are commonly used animal models for regenerative endodontics research.
Salamanders have a remarkable capacity to regenerate complex tissues, such as limbs and brain, and are therefore an important comparative model system for regenerative medicine.
Zebrafish are able to regenerate different organs after injury, including heart, fins, retina, liver, and spinal cord, and have become a powerful model organism for regenerative studies [ 1- 5].
The zebrafish has become a powerful model for investigating regenerative processes because of its capacity to completely repair several organs, including the heart, after injury (Gemberling et al., 2013).
We first describe the overall system model for non-regenerative multi-way relaying.
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