This difference may reflect the incomplete reprogramming of iPS cells and should be critically considered in further studies to clarify the suitability of the iPS model for regenerative medicine of heart disorders.
Therefore, this study aimed to characterize the dental pulp stem cells isolated from dog teeth (cDPSCs) in order to further define the dog as an animal model for regenerative endodontics.
The medusazoan model system, Hydra, has long been a comparative model for regenerative study, bridging the gap between early animals, planarians, flies and vertebrates.
As well, advances in induced pluripotent stem cell (iPSCs) technologies [ 6- 8] make the pig an attractive model for regenerative medicine and stem cell research.
Likewise, the maxillary sinus of rabbits is considered to be a good experimental model for regenerative studies following sinus surgery [ 27– 33].
These results suggest that the telencephalic VZ contributes to neural tissue recovery following telencephalic injury in the adult zebrafish, and that the adult zebrafish is a useful model for regenerative medicine.
So far, our results indicated that hPLAP-tg rats could serve as a very attractive model for regenerative therapies because of ubiquitous and strong expression of the transgene, and excellent preservation of the marker enzyme in paraffin and MMA sections.
To test the idea of employing marker tolerant animals as a model for regenerative therapies, we initially used lethal irradiation and transplantation of bone marrow from hPLAP-tg F344 rats into wild-type F344 rats as proof-of-principle to prevent the immune response after injection of transgenic cells into wild-type rats.
With their low catalytic over-potential5, [FeFe]-hydrogenases represent excellent models for a regenerative and likewise economically feasible H2 production.
This review analyzes animal models for skin regenerative healing in a variety of vertebrates, including fish, amphibians, reptiles, and mammals.
