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First, we used the chicken chorioallantoic membrane (CAM) model, an established preclinical tumor model, for example, for glioblastoma.
To address this question we used the chicken chorioallantoic membrane (CAM) model, an established preclinical tumor model.
This is essentially a generalized animal model, an established quantitative genetic method that has been used extensively to model biological and disease phenotypes.
The authors again used the N-nitrosomethylurea (NMU) rat model, an established model for breast cancer development and progression that produces hormone-dependent tumors [ 27] and has been used successfully to predict the efficacy of chemopreventive hormonal agents.
To investigate whether ABT-737 enhances TRAIL-induced cell death not only in monolayer cultures in vitro but also in a three-dimensional tumor model in vivo, we used the chorioallantoic membrane (CAM) model, an established in vivo tumor model, for example, for anticancer drug testing.
Here we employ, for this purpose, the quasispecies model, an established model of intrahost viral evolution (Eigen and Schuster 1977; Burch and Chao 2000; Vignuzzi et al. 2005; Metzner et al. 2009; Domingo et al. 2012), which is mathematically tractable.
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The PA-1 tumor model is an established xenograft model for ovarian cancer [ 37, 38, 39, 41, 42].
This model utilises an established quality improvement methodology, DUE, as described previously.
Workflow modelling is an established technique for business process re-engineering.
Desire was scored using an established model called the Female Sexual Function Index, which ranges from 1.2 to 6.0.
Wound healing is an established model system for detecting TG2 activity [33].
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