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Because there isn't, for example, an established blueprint for how to run an e-commerce business, we often learn things as we go.
What value would you get by partnering or buying – for example, an established industry reputation, media relationships or SEO links – that you couldn't build from scratch?
Let's take for example, an established conservation area in Indonesia that is home to orangutans, Sun bears, gibbons and the rare and endangered Storm's stork.
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For example, in an established murine fibrosarcoma model, the maintenance of M2-phenotype was associated with defective NF-κB activation.
"Going overseas is fine but where is this example of an established Premiership coach failing as the England coach?
George Osborne's use of the six dead Philpott children to promote his own agenda was simply another example of an established political device – the manipulation of the voiceless.
If you're looking for an example of an established company successfully adapting to trends, look no further than McDonald's.
When Bitcoin, as a primary example of an established cryptocurrency, started making headlines in mainstream media, a lot of the reporting was about how this magically decentralized form of money could bypass banks and render them obsolete.
Magnetoencephalography (MEG), for example, is an established (usually non-optical) technique for imaging sources of magnetic fields inside the brain.
Our continuing difficulty in dealing with patients presenting with chronic cough is an example of an established dogma failing to measure up to awkward clinical facts.
IBM is an example of an established multinational corporation that successfully incorporated the provision of open software support services into its business model and its employees actively contribute to open software development.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com