Sentence examples for minimum drug concentration from inspiring English sources

The 50% inhibitory concentration (IC50), i.e. the minimum drug concentration that caused a 50% reduction in survival/viability in comparison with that in identical cultures without the compound, was evaluated after 48 hours for the most effective PIs.

For the mean flow rate of the LAD denoted as Re0, there was about a 50-fold difference between the maximum and minimum drug concentration in the proximal segment of the stent.

MICs were determined visually as the minimum drug concentration that prevented the growth of cord structures.

The minimal inhibitory concentration (MIC) was defined as the minimum drug concentration that prevented the color change in resazurin solution.

Color change of the medium was used to estimate the minimum drug concentration that could inhibit M. pneumoniae growth (MIC).

When we tested the n = 3 network, we obtained the same results when we used either I = 0.0000 or I = 0.0001 (10-4) as the minimum drug concentration.

This effect amplifies the change in drug delivered to and penetrating into the inter-strut arterial segments, raising drug levels in these regions and reducing the range between local maximum and minimum drug concentrations.

Similar trends were observed for minimum (trough) drug concentration (Ctrough) and maximum drug concentration (Cmax).

Compared with IR CD-LD, IPX066 also reduced the levodopa Cmax/ Cmin (minimum plasma drug concentration) ratio (12.0 ± 18.5 vs. 82.2 ± 67.5) and fluctuation index (1.5 ± 0.4 vs. 3.2 ± 1.3) at steady state.

It was suggested that there may be a minimum plasma drug concentration (between 0.5 and 1 ng/ml [ 19] for optimal anthelmintic activity against susceptible gastrointestinal or lung nematodes. However, the existence of such a minimum effective concentration has not been confirmed.

It is well established that serum Cmax/MIC (ratio of maximum drug concentration to minimum inhibitory concentration) >8 and AUC/MIC (ratio of area under the concentration-time curve to minimum inhibitory concentration) >100 are required for efficient and optimal pharmacotherapy of enrofloxacin [ 11].