Sentence examples for minimize the induction from inspiring English sources

A major challenge in developing the checkpoint-based therapy for autoimmune diseases is identifying pathways that will minimize the induction of adverse global immune suppression that impairs the host protective immunity against cancer and microbial pathogens.

We found that a 50 ng/ml dose of CyaA was optimal to maximize the induction of intracellular cAMP and to minimize the induction of apoptosis (data not shown).

With respect to the excess of signaling pathways downstream of certain kinases, selective tyrosine kinase inhibitors have some advantages in order to minimize the induction of toxicities.

The spider mite Tetranychus evansi, for example, is able to minimize the induction of direct (proteinase inhibitor accumulation) and indirect (volatile emission) defenses in tomato plants [ 88].

It was proved that superficially attacking the synthetic jarosite with arsenic in HNO3 (a way to create defects or to remove submicron films) minimizes the induction period.

First, concerning thromboembolism risk, transdermal estradiol avoids the "first-pass" effect, thus minimizing the induction of clotting factors by the liver.

We agree with Dr Collignon that convincing data indicate that use of antimicrobial agents that are of human importance among food animals has an adverse human health impact and that the time has come to find alternatives that promote food-animal health while minimizing the induction of antimicrobial resistance.

This procedure should help to minimize the artificial induction of stress-responsive genes during the experiments.

The ability to target the molecular changes occurring at the earliest phase of pain induction following immune system activation could minimize the involvement of the downstream nociceptive mediators involved in the induction and/or maintenance of chronic pain.

This may be due to the high basal expression displayed by the native osmotin promoter in the absence of ERF effectors, which likely minimizes the induction effect observed in the presence of ERFs (Additional file 3).

The induction of molecular chaperones can minimize the accumulation of damaged proteins by enhancing their refolding and interfering with pro-apoptotic pathways (Brown, 2007).